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Prof. Dr. Olivia Merkel

Address

Prof. Dr. Olivia Merkel
Department Pharmazie
Ludwig-Maximilians-Universität München
Butenandtstr. 5-13, Haus B
81377 München
Germany

Phone +49 89 2180 77025
Fax +49 89 2180 77020
Room-Nr. B1.026
Email olivia.merkel@cup.uni-muenchen.de
Home page www.cup.lmu.de/pb/aks/merkel

Research Interests

  • Non-viral siRNA Delivery
  • T Cell Targeting
  • Macrophage Targeting
  • Molecular Treatments for Lung Diseases
  • Molecular Treatments for Inflammatory Diseases
  • Molecular Treatments addressing Cancer Immunology
  • Smart Dosage Forms

Short CV

  • Since 2015 Interim Professor of Drug Delivery, LMU Munich, Germany
  • Since 2012 Associate Faculty of Oncology, Wayne State University
  • Since 2011 Tenure-Track Professor of Pharmaceutics, Wayne State University
  • 2009-2011 Postdoc/Habil Cand, Philipps-Universität Marburg, Germany
  • 2009 PhD in Pharmaceutics, Philipps-Universität Marburg, Germany
  • 2006 MS in Pharmaceutics, Martin-Luther-Universität Halle, Germany
  • 2005 Board License as Pharmacist, Philipps-Universität Marburg, Germany

Key publications

  • Yuran Xie, Na Hyung Kim, Venkatareddy Nadithe, Dana Schalk, Archana Thakur, Ayşe Kılıç, Lawrence G Lum, David JP Bassett, Olivia M Merkel*: Targeted delivery of siRNA to activated T cells via transferrin-polyethyleneimine (Tf-PEI) as a potential therapy of asthma. Journal of Controlled Release, 2016, doi:10.1016/j.jconrel.2016.03.029 <http://www.sciencedirect.com/science/article/pii/S0168365916301638>
  • Steven K Jones, Vincent Lizzio, Olivia M Merkel*: Folate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Copolymer to Overcome TLR4 Driven Chemotherapy Resistance. Biomacromolecules, 2016, 17 (1), 76-87 <http://pubs.acs.org/doi/abs/10.1021/acs.biomac.5b01189>
  • Li Liu, Mengyao Zheng, Damiano Librizzi, Thomas Renette, Olivia M Merkel*, Thomas Kissel: Efficient and Tumor Targeted siRNA Delivery by Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate (PEI-PCL-PEG-Fol). Molecular Pharmaceutics, 2016, 13 (1), 134-43 <http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.5b00575>
  • Maha Elsayed, Vincent Corrand, Vidula Kolhatkar, Yuran Xie, Na Hyung Kim, Rohit Kolhatkar, Olivia M Merkel: The influence of oligospermine architecture on their suitability for siRNA delivery Biomacromolecules 2014, 15 (4), 1299-1310 <http://pubs.acs.org/doi/abs/10.1021/bm401849d>
  • Mengyao Zheng, Giovanni M. Pavan, Manuel Neeb, Andreas Schaper, Andrea Danani, Gerhard Klebe, Olivia M. Merkel*, Thomas Kissel: Targeting the blind spot of polycationic nanocarrier-based siRNA delivery ACS Nano 2012, 6(11), 9447-54 <http://pubs.acs.org/doi/abs/10.1021/nn301966r>