Warning: Undefined array key "HTTP_ACCEPT_LANGUAGE" in /home/webdocs/site/assets/cache/FileCompiler/site/templates/_init.php on line 36
Deprecated: substr(): Passing null to parameter #1 ($string) of type string is deprecated in /home/webdocs/site/assets/cache/FileCompiler/site/templates/_init.php on line 36 Faculty for Chemistry and Pharmacy LMU Munich - Semester events
Title: Self-healing dyes – new promise in live cell imaging
Abstract:
Phototoxicity and photobleaching have become prevailing issues in the advanced imaging era when boosted illumination is applied, compromising both the acquisition window and the physiological relevance of the recorded data. We advocate leveraging chemical approaches to tackle phototoxicity and photobleaching. I will introduce our recent work on exploiting phenyloxadiazole (POD)-based chemistry to label cysteine which alleviate photobleaching, and discuss the new and general applications of cyclooctatetraene (COT) -conjugated cyanine dyes in time-lapse live cell imaging. For example, we present PK Mito Orange probe, a mitochondrial inner membrane stain that enables 30 frames of STED recording and multi-color imaging of mitochondrial components.
Vortrag,
Prof. Trapp, OC 11:00, Baeyer-Hörsaal
Merck-Banyu Lectureship Award 2021 und 2022
Prof. Dr. Masakazu NAMBO, Institute of Transformative Bio-Molecules, Nagoya University, Japan (winner 2021) New Transformations of Organosulfones through C–SO2 Bond Activation
Prof. Dr. Kenzo YAMATSUGU, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan (winner 2022) Chemical Catalysis Enabling Synthetic Intervention in Cellular Epigenome
jointly organized by the Ludwig Maximilian University of Munich and Merck Life Science KGaA with the collaboration of the MChG
08:30 - 09:00: Registration
09:00 - 09:20: Welcome by Merck KGaA, Anja Hoffmann-Röder (LMU) and Dominik Leitz (MChG)
09:20 - 10:15: Lecture - Dr. Kenneth Schwieter - Head of Product Marketing, Chemical Synthesis and Discovery Chemistry - Merck KGaA - "New Tools for Chemical Synthesis"
10:15 - 10:45: Coffee break
10:45 - 11:40: Lecture - Prof. Adriaan J. Minnaard - Stratingh Institute of Chemistry - University of Groningen - "Synthesis-driven natural product chemistry"
11:40 - 12:15: European Retrosynthesis Competition Prize ceremony and winner's lecture
12:15 - 15:00: Lunch break and poster session
15:00 - 15:35: Lecture - Dr. Golo Storch - Department of Chemistry - Technical University of Munich - "Flavin catalysis as a versatile tool in synthetic organic chemistry"
15:35 - 16:10: Lecture - Dr. Fumito Saito - Department of Chemistry - Ludwig Maximilian University Munich - "One-step, three-component synthesis of sulfur functional groups"
16:10 - 17:10: Lecture - Prof. Paul Knochel - Department of Chemistry - Ludwig Maximilian University Munich - "Li, Na, Mg and Zn-organometallics for organic synthesis"
Thu, Oct 12, 2023
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Prof. Dietmar Trenk
(FESCK Klinische Pharmakologie, Klinik für Kardiologie und Angiologie Universitätsklinikum Freiburg, Universitäts-Herzzentrum Bad Krozingen)
Chronische Herzinsuffizienz - Therapie im Umbruch
Thu, Nov 23, 2023
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Richard Merrill, LMU
Adaptive introgression of a visual preference gene
Festveranstaltung zur Überreichung der Master-Zeugnisse in Chemie und Biochemie sowie der Römer-Preise 2023
15:15 Uhr Festveranstaltung zur Überreichung der Master-Zeugnisse in Chemie und Biochemie sowie der Römer-Preise 2023
17:00 Uhr Römer-Lecture: Chaperone in der Zelle: Die Rolle bei Gesundheit und Krankheit;
Prof. Dr. Ulrich Hartl, Max-Planck-Insitut für Biochemie, Abt. Zelluläre Biochemie
Mon, Dec 04, 2023
Symposium,
SFB 1309 09:00, Building L, conference room (L00.010)
"Understanding an undeclared nuclear accident: The mysterious release of ruthenium-106 in 2017"
Wed, Jan 10, 2024
Symposium,
Dept. Chemie 13:00, Zoom-Meeting
Online-Symposium Spektroskopische und medizinische bioanorganische Chemie
13:00 – 13:30 Advanced EPR Spectroscopies to Elucidate Biological Active-Sites. 14:10 – 14:40 The underestimated Potential of Metal Complexes in Medicine. 15:20 – 15:50 From electron spins to structure and function: Exploring bioinorganic radicals with spectroscopy.
Dr. Malte Gersch, the Max-Planck-Institute of Molecular Physiology, Chemical Genomic Centre
"Decoding ubiquitin signaling with chemical biology"
Tue, Jan 16, 2024
Symposium,
Dept. Chemie 13:00, Zoom Meeting
Online-Symposium Spektroskopische und medizinische bioanorganische Chemie
13:00 – 13:30 Bioinspired Oxidation Chemistry: From Functional Models towards Catalysis. 14:10 – 14:40 EPR methodology to investigate active metal sites 15:20 – 15:50 Electron Paramagnetic Resonance as a Toolbox to Study Bioinspired Metal-Based Catalysis and Biochemical Processes. 16:30 – 17:00 Engineering Nitrogenases for a new Route of CO2Conversion – Investigating the Origin, Evolution and Mechanism of Metalloenzymes.
Navigating the crossroads between chemistry and mathematics – how much is actually “just maths”?
Fri, Jan 26, 2024
Symposium,
Prof. Thomas Bein 09:45, -15:30 Butenandt Hörsaal 16:15-17:30 Buchner Hörsaal
Adventures in Nanoscience
Alumni-Symposium - Thomas Bein Group
and Keynote Lecture
09:45-10:00 h Welcome (Butenandt lecture hall)
10:00-12:00 h Lectures: Porous Materials - from Drug Delivery to Catalysis and Energy Conversion
Prof. Valentina Cauda, Politecnico de Torino, Italy "Bioinspired nanovesicles as bioengineered hybrid tools against cancer cells" Prof. Hanna Engelke, University of Graz, Austria "Nanomaterials meet biology" Prof. Stefan Wuttke, BCMaterials, Leioa, Spain "Plenty of room at the top" Dr. Dana Medina, LMU Munich, Germany "On-surface molecular frameworks – synthesis, properties and function" Prof. Norbert Stock, University of Kiel, Germany "The making of MOFs 10 years on - a personal update!" Prof. David Gardner, Lander University Greenwod, SC, USA "Nanoscience and lessons from red velvet cake: Developing the next generation of scientists"
13:30-15:30 h Lectures - continued (Butenandt lecture hall)
Prof. Dina Fattakhova-Rohlfing, FZ Jülich, U. Duisburg-Essen, "There and back again across the Weißwurst-equator: a journey from functional nanomaterials to functioning devices" Dr. Jenny Schneider, LMU Munich, Germany "Tracking light-induced charge carriers in photocatalysis" Dr. Florian Auras, TU Dresden, Germany "Controlling the structure and electronic landscape of organic semiconductors" Prof. Wolfgang Tress, ZHAW Winterthur, Switzerland "Uncovering the bottlenecks in perovskite solar cell performance" Prof. Askhat Jumabekov, Nazarbayev University in Astana, Kazakhstan "Optimizing perovskite optoelectronics: Advancing device architecture" Prof. Dirk de Vos, Katholieke Universiteit Leuven, Leuven, Belgium "Into the borderlands of (homogeneous) catalysis and porous materials science"
16:15-17:30 h Keynote Lecture (Buchner lecture hall)
Prof. Bettina Lotsch (MPI for Solid State Research, Stuttgart, Germany) "Covalent Organic Frameworks for Solar Energy Conversion: From Design to Function"
Title: Approaches to the design of protein folds and functions
Abstract: In protein design we aim to build new proteins with novel functions. Methods range from generating and screening of mutant libraries via repurposing of active sites or binding pockets all the way to de novo design. In many of these approaches protein structures form the basis for the designs and structures are solved to validate the hypotheses. I will discuss advantages and difficulties of the different approaches and show some highlights from our recent work that range from biosensors to the de novo design of TIM-barrels. As structure prediction and design are greatly influenced by the rapidly developing AI-based methods, I will also touch on this topic, in particular the use of natural language processing.
DPhG-Vortrag,
Dept. Pharmazie 18:30, Raum F0.001
Prof. Anette-Gabriele Ziegler
(Direktorin des Instituts für Diabetesforschung, Helmholtz-Zentrum München, DFZ für Gesundheit und Umwelt)
Früherkennung und Prävention von Typ 1-Diabetes
Thu, Feb 01, 2024
IMPRS Lecture Series,
MPI of Biochemistry 17:00, Martinsried T-Building, Large Lecture Hall
Karsten Borgwardt, MPIB
Machine learning in systems biology: Current challenges and future goals
Symposium,
Gene Center Munich 09:00, Römer-Forum (K00.015)
SYMPOSIUM New Frontiers in Nucleic Acid Research
9:00 am
Dr. Pengbiao Xu Swiss Federal Institute of Technology Lausanne
Structural basis of nuclear cGAS inhibition and degradation
9:35 am
Dr. Markus Höpfler MRC Laboratory of Molecular Biology Cambridge
Mechanism of selective mRNA degradation at the ribosome
10:10 am
Dr. Chris Carnie Cancer Research UK Cambridge Institute
Metabolic determinants and molecular mechanisms of DNA damage and repair
Coffee break
11:05 am
Dr. Alessandra Brambati Memorial Sloan Kettering Cancer Center New York
Balancing act: the role of non-canonical DSB repair pathways in genome stability and diversity
11:40 am
Dr. Jonathan Bohlen Institut Imagine (INSERM) Paris
Requirements and regulation of mRNA translation in human leukocytes and immunity
Prof. Dr. Marisa Kozlowski, University of Pennsylvania, College of Arts & Sciences
Oxygen Driven Fragment Coupling for the Synthesis of Natural Products and Antibacterials
Abstract: Nature uses oxidative couplings to construct carbon-carbon, carbon-oxygen, and carbon-nitrogen bonds with a high degree of efficiency. Surprisingly, few laboratory equivalents are as selective or as efficient as the biological versions. The use of parallel microscale screening to discover selective and efficient catalysts for such processes using oxygen as the terminal oxidant will be discussed. The unexpected outcomes obtained highlight the value of interrogating large numbers of rationally selected variables under the umbrella of general hypothesis. The development of selective oxidative catalytic processes for phenol coupling, enol coupling, and alkyl C–H activation will be discussed. Applications in total synthesis of hypocrellin, honokiol, chaetoglobin, and pyrolaside B will be presented. Finally, studies on the mechanisms of these transformations will be described with the goal of understanding the governing principles and how they might be used to discover further new transformations.